George Samuel Bailey joined the faculty of the Oregon State University Department of Food Science and Technology in 1979 to research the role of dietary phytochemicals in inhibiting cancer growth using both trout and human models. Bailey continued studies begun at Oregon State in the 1960s on the carcinogen aflatoxin and rainbow trout; his major contribution was the discovery that chlorophyllin acts to inhibit aflatoxin uptake in the body. Bailey served as director of the OSU Marine and Freshwater Biomedical Sciences Center from 1985 to 2002 and served on the faculty advisory committee that assisted with establishment of the Linus Pauling Institute at OSU in 1996. Bailey was recognized for his research and service with his appointment as Distinguished Professor of Environmental and Molecular Toxicology in 1998. He retired in 2008.
Bailey earned a BS in chemistry at the University of Southern California (1965) and Ph.D. in biochemistry from the University of California at Berkeley (1969). During his research career, he published more than 150 papers in peer-reviewed scientific journals and mentored many graduate students at Oregon State University.
The George S. Bailey Papers document research conducted by Bailey and several research faculty, graduate students, and postdoctoral researchers working under his direciton on dietary cancer prevention agents. The research focussed on the mechanisms whereby chlorophylls (specifically chlorophyliin) and indoles inhibit the carcinogens Aflatoxin B1 and Dibenzo(a,1,)pyrene (DBP) in trout. Research with zebrafish is also reflected in the records.
The Papers include research and laboratory notebooks, correspondence, drafts of articles, manuals, photographs, reference materials, research data, and theses. The research and laboratory notebooks include research data, laboratory procedures (such as PCR), and reference materials. The research data include sequenced gels containing DNA information. The photographs consist of color slides of trout specimens, chlorphyll, charts and graphs of research data, and researchers at work in the laboratory.
Graduate students and researchers whose work comprise a substantial component of the papers include Vibeke Breinholt, R.H. Dashwood, Patricia M. Loveland, Patricia O'Neal-Tragen, Ashok P. Reddy, and Lijing You. Aflatoxin research conducted prior to Bailey's arrival at OSU in 1979 is available in the research notebooks of Patricia Loveland, Norman E. Pawlowski, and David Jones.