UUM_Accn2676.xml Inventory of the Don B. Olsen papers Olsen (Don B.) papers Finding aid created by Betsey Welland. J. Willard Marriott Library Special Collections

2013 (last modified: 2020)
295 South 1500 East Salt Lake City, Utah 84112 Business Number: 801-581-8863 special@library.utah.edu https://lib.utah.edu/collections/special-collections/index.php
This finding aid was produced using ArchivesSpace on 2025-10-23. Finding aid written in English. Finding aid based on DACS (Describing Archives: A Content Standard), 2nd Edition. J. Willard Marriott Library Special Collections Don B. Olsen papers Olsen, Don B. (Donald B.), 1930-2018 ACCN 2676 44.5 linear feet 95 boxes 1839-2012 The Don Olsen papers (1839-2012) contain materials regarding artificial organ projects and consist of professional and administrative materials, business files, subject files, and professional writings by Olsen. Olsen was a distinguished professor at the University of Utah and a medical researcher specializing in the artificial heart. English

Dr. Olsen received a D.V.M. from Colorado State University, a B.S. in Animal Nutrition and Chemistry from Utah State University, and he attended the University of Nevada. A postdoctoral fellowship to the University of Colorado, Department of Pathology funded research on electron microscopic demonstrations of lung surfactant and its intracellular synthesis and secretion; and he served on collaborative research projects such as the study of the artificial heart valve in the calf, electrophysiology of the heart, and electrical pacemaker evaluation.

Seven years of general veterinary practice followed graduation, but Dr. Olsen's main interest was in basic and applied research. He studied diseases of cattle and sheep at the University of Nevada. As Principal Investigator of government and private grants he studied bovine fetal hemodynamics, blood flow, hypertension, and complete heart—block in sheep, receiving the Hancock Foundation Research Award for cardiovascular research to study the use of digitalis in sheep having induced heart failure, and Life Sciences Research Fund for preliminary investigation of acute bovine emphysema induced by terpene (a naturally occurring compound in forage plants).

Dr. Olsen lectures and conducts seminars internationally. In 1976 he had the opportunity to lecture for six weeks in medical schools and artificial heart research centers in Germany, Austria, France, and Italy. In 1977 he served a year on a Distinguished Scientist Award fellowship from the Von Humbolt Foundation in Munich and Berlin. He also lectured and presented demonstrations of implantation techniques in Czechoslovakia, Vienna, Austria, Brno, and Lyon, France. Several years later he implanted a record surviving calf (15 days) in Rostock, East Germany.

He joined the University of Utah as Assistant Director of the Division of Artificial Organs in 1972. Many changes occurred to lengthen the survival times of animals implanted with a total artificial heart, leading to world-record survival times. While heading the surgery team, Dr. Olsen modified the surgical implantation technique then used (midsternal split) to a lateral thoracotomy procedure to implant the newly modified Jarvik ventricles. Modified surgical techniques dramatically improved and simplified the early postoperative management of the animals. Survival increased to 3 months in 1974 (BURKE, calf), to later records set by TENNYSON, MAGIC, BIG AL (calves, 268 days), TERRY (calf, 272 days) and TED E. BEAR (sheep, 297 days).

In 1974 and 1975, Dr. Olsen developed an innovative technique, excising the heart and retaining the natural pulmonary artery and aortic valves, so the artificial heart required only two artificial valves. The first calf to retain its natural outflow valves was a world-recording holding animal (4 months in late 1975) using the JARVIK-5 ventricle, and the record holding sheep was TED E. BEAR (297 days). To date, other laboratories have not been as successful in using sheep in total artificial heart and left ventricular assist device experiments. The combination of excellent and innovative surgical techniques coupled with modified ventricular designs resulted in superior fit in the chest of the animal, larger stroke volumes, faster postoperative recovery times, and more durable artificial ventricles, leading to the vastly extended survival times.

These modified surgical techniques, along with subsequent training of clinical surgeons in implant techniques of the artificial heart, culminated in the implantation of the artificial heart in a human: Dr. Barney Clark. Dr. Olsen assisted Dr. William DeVries and Dr. Lyle Joyce in this momentous surgery in December 1982. Additionally, the majority of surgical teams in the world implanting the artificial heart were trained by Dr. Olsen and his research team at the Artificial Heart Research Laboratory.

In October 1979 a transplantation program was begun. Twin calves were used to study the feasibility of placing a natural heart into a calf after it had been implanted with an artificial heart for periods upwards of four months (immunosuppression problems are eliminated using the chimeric twin of the animal). FERNANDO survived for a year in good health after being transplanted with his chimeric twin's heart. After implantation with an artificial heart for 74 days, CHARLEY's (weight 220 pounds) artificial heart was removed and his twin sister DIANE's natural heart transplanted. CHARLEY outgrew the laboratory's farm facilities in 15 months and was placed as a dairy herd sire, fathering over 55 calves. Then he was slaughtered for beef 39 months after cardiac transplantation (weight 1,785 pounds).

Also, exercise regimens were implemented for the artificial heart animals using specially constructed treadmills, and some experiments were done without anticoagulants. Dr. Olsen also did specific investigation into coronary vein perfusion, the living A-V fistula, continuing to be particularly interested in the effect of the artificial heart upon the lungs.

In February 1986 the directorship of the Institute for Biomedical Engineering, College of Engineering and Department of Surgery, was transferred to Dr. Olsen when Willem J. Kolff retired February 14 (Dr. Kolff is known as the "Father of Artificial Organs," and had established the department two decades earlier at the University of Utah). Prior to this Dr. Olsen was Head of the Artificial Heart Research Laboratory, Division of Artificial Organs, Department of Surgery, and continues in this position.

He was instrumental in forming the Murex Foundation, a receiving company for private donations for the Institute; and through his efforts obtained donation to the Institute for Biomedical Engineering of the building complex where sizeable, off-campus laboratories are located; subsequently forming another receiving company, the MedForte Foundation, for transferrance of income from this complex to the Institute.

In 1988 Dr. Olsen was elected Program Chairman of the American Society for Artificial Internal Organs for the following year, and has been on their Fellowship Review Committee since 1983. Editorial experience includes: Associate Editor, ASAIO Journal; Editorial Reviewer, Artificial Organs; and Editorial Reviewer, American Journal of Veterinary Research.

Dr. Olsen is married and the father of five children. He is an enthusiastic deer, elk, antelope and moose hunter in Utah, Oregon, Canada, and Alaska, enjoys cross—country skiing, fishing and hiking.

(This biography was taken from a biographical sketch created by Don B. Olsen.)

The Don Olsen papers (1839-2012) contain information regarding artificial organ projects and consist of professional and administrative materials, business files, subject files, and professional writings by Olsen. The collection has been divided into 5 sections.

The first section contains personal and administrative materials focusing on Olsen's professional career. Materials include patent applications, conference materials, grant and funding documentation, and biographical information.

The second section contains professional writings by Olsen and also writings he co-authored.

The third section consists of files Olsen collected on various individuals. These folders are arranged alphabetically by last name and contain correspondence, research articles, and other materials.

The fourth section consists of business files and other organizational records maintained by Olsen. Included in these folders are materials regarding the business itself or materials regarding Olsen's involvement with such businesses.

The fifth section contains research materials and are organized by subject. Olsen collected research materials on such topics as the total artificial heart, continuous-flow ventricular assist devices, the electrohydraulic total artificial heart, and physiologic controllers. General subject files have been arranged alphabetically.

This collection was organized into five series: I. Professional and administrative; II. Writings; III. People files; IV. Business files; V. Research materials.

Original folder titles provided by the creator of the collection have been maintained.

Twenty-four hour advanced notice encouraged. Materials must be used on-site. Access to parts of this collection may be restricted under provisions of state or federal law.

The library does not claim to control copyright for all materials in the collection. An individual depicted in a reproduction has privacy rights as outlined in Title 45 CFR, part 46 (Protection of Human Subjects). For further information, please review the J. Willard Marriott Library's Use Agreement and Reproduction Request forms.

Collection Name, Collection Number, Box Number, Folder Number. Special Collections, J. Willard Marriott Library, The University of Utah.

Donated by Don B. Olsen in 2012.

Processed by Betsey Welland in 2012-2013.

Photographs and audio-visual materials were transferred to the Multimedia Division of Special Collections.

See also the Willem J. Kolff papers (MS 0654), the Barney B. Clark papers (MS 0670), and the Theodore H. Stanley papers (ACCN 3106) all located in the Manuscripts Division of Special Collections.

 Olsen, Don B. (Donald B.), 1930-2018--Archives University of Utah--Faculty Heart, Artificial--Research--Utah Artificial organs--Research--Utah Veterinarians--Utah Articles Correspondence Reports Professional and Administrative 1966-2012 I Professional materials Correspondence 1983-2010 1 1 Curriculum vitae 2011 1 2 Goals and objectives 1974-1994 1 3 Dates and timelines 2001-2004 1 4 Contracts 1970-1986 1 5 Airline travel records 1984-2000 1 6 Responses to applicants 1988-1991 1 7 Administrative and general materials Artificial Heat Team meeting 1981-1984 2 1 Conference call notes 2006 2008 2 2 Gifting of the Northgate Business Complex 1987-1988 2 3 Hastings lecture 1984 1999 2 4 IAB study 1991 2 5 Patient consent forms 2010 2 6 Project review 2009-2010 2 7 Student science packets 1986-1989 2 8 Surgery class 1988-1989 2 9 Grant projects Abstract for the American College of Chest Physicians 1972 3 1 Acute phase inflammatory response to blood pumps 1993 3 2 Assessment of flow method for infant ventricular assist 1994 3 3 De-heparinized filter 1993 3 4 Fort Collins 1972 3 5 Hemodynamic and fluid derangement with artificial hearts 1993-1995 3 6 Thrombogenesis renewal 1993 3 7 Tim Baldwin 2012 3 8 Utah-100 1992-1993 3 9-10 Utah continuous flow ventricular assist device proposal 1996 3 11 General grant materials Fund raising 1976-2007 5 Earl E. Bakken 1994-1995 5 1 Dale E. Ballard 1995 5 2 Shawn Bradley 1993-1996 5 3 O. H. "Bud" Frazier 2007 5 4 Genevieve Gore 1976-1995 5 5 Robert Hinckley 1992-1993 5 6 Kenneth H. Olsen 1987-2000 5 7 Kenneth A. Solen 1988-2007 5 8 James Sorenson 2002-2003 5 9 General materials 1998 2005 5 10 Contributions Thomas W. Crosswhite 1998 6 1 Baxter Healthcare Corp. 1998 6 2 Ventricular Assist Device (VAD) and Total Artificial Heart (TAH) funding 1995 6 3 Request for fund raising approval 1990 6 4 General materials 1995-1999 6 5 Patent applications Axial-flow blood pump with magnetically suspended, radially and axially stabilized impeller 2004-2007 7 1-2 Development of a biventricular replacement device 1986 7 3 Blood pumps 1987-2000 7 4 Electromagnetically suspended and rotated centrifugal pumping apparatus and method 1996-1997 8 1 Hybrid magnetically and rotated centrifugal pumping apparatus and method 1997-1999 8 2 An implantable centrifugal blood pump with hybrid magnetic bearings 1998 8 3 MSRBP 1984-2006 8 4 MedQuest Products (MQP), University of Virginia (UVA), and Utah Artificial Heart Institute (UAHI) 1995-2002 9 1 Permanent magnet or permanent magnet array having a uniform flux density 2007-2008 9 2-3 Streamlined unobstructed one-pass axial flow pump 1996-2007 9 4 Ventricular assist device with volume displacement chamber 1987-1995 9 5 General patent materials and disclosures 1984-2001 10 Conference materials Bioengineering research partnership grantee meeting 2006 11 1 Concerted Action Heart Phase II 1993 11 2 Conference on Cardiovascular Science and Technology 1990 11 3 Heart Failure and Rotary Blood Pump Summit 2004 11 4 International Conference on Circulatory Support Devices for Severe Cardiac Failure 1994 11 5 International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion 2005-2006 11 6-7 International Symposium on Artificial Organs, Biomedical Engineering and Transplantation in Honor of the 75th Birthday of W. J. Kolff 1984-1988 12 1-2 International Symposium on Artificial Heart and Assist Devices 1996 12 3 International Society for Rotary Blood Pumps and Artificial Organs 1993-2008 12 4-6 International Workshop on Rotary Blood Pumps and Artificial Organs 1988-2006 12 7-8 National Heart, Lung, and Blood Institute Conference 1992 13 1 Scientific Conference 2005-2007 13 2-4

Honoring Donald B. Doty, Reed M. Gardner, T. Allan Pryor, and L. George Veasy

 Technology Assessment Conference on Improving Medical Implant Performance Through Retrieval Information 2000 13 5 Utah State Centennial Centerpiece 1988 13 6 Writings II Writings by Olsen "Artificial Heart Effects on Organ Function" 1985 14 1 "Artificial Organs of the Future" 1992 14 2 "Bridge-to-Transplant Experience with the Jarvik-7 and the Jarvik-7-70 Total Artificial Heart" 1987 14 3 "Cardiopulmonary Bypass for Implantation of an Artificial Heart and for Cardiac Transplantation" 1985 14 4 "Current and Future Valves for Blood Pumps" 1988 14 5 "Does the Artificial Heart Work? Experimental and Clinical" 1987 14 6 "Dr. Willem J. (Pim) Kolff: The Legend, My Mentor" 1998 14 7 "The FDA and the Artificial Heart" 1990 14 8 "The Future Roll of Classified or Proprietary Research at Utah State University" 1988 14 9 "The History of Continuous-Flow Blood Pumps" 2000 14 10 "Improved Artificial Hearts for People Through Creative Research" 1988 14 11 "Intraoperative and Postoperative Patient Monitoring During Thoracic Surgery" 1978 14 12 "Letter to Editor Regarding Fundamental Rhythm of Sympathetic Nerve Discharges in Animals with Total Artificial Hearts" 1995 14 13 "Letter to Editor Regarding Physiological Control of Cardiac Assist Devices" 1996 14 14 "Mechanical Circulatory Bridging to Cardiac Transplantation" 1995 14 15 "Perfecting the Artificial Heart Technology in Animals" 1983 14 16 "Rotary Pump and Cardiac Assist, Early to Present" 14 17 "Rotary Blood Pumps: A New Horizon" 1999 14 18 "A Short Summary of Contributions to the University of Utah By the Institute for Biomedical Engineering Artificial Heart Research Laboratory" 1992 14 19 "The Total Artificial Heart: Yesterday, Today, Tomorrow" 1981 14 20 "Understanding Critical Patient Care Via the Artificial Heart" 1987 14 21 "The Use of Sheep in Cardiovascular Research" 1980 14 22 Writings by Olsen with others Hee Chan Kim et al., "Adaptive Full-Ejection Point Detection for Automatic Control of the Electrohydraulic Total Artificial Heart" 1993 15 1 Robert K. Jarvik et al., "After Two Decades of Research - Six Months' Survival with the Total Artificial Heart" 1977 15 2 Bang-Yu Chiang et al., "An Analysis of Animals Surviving Over One Hundred Days on the Total Artificial Heart" 1983 15 3 Don B. Olsen et al., "Artificial Heart Implantation, Later Cardiac Transplantation in the Calf" 1981 15 4 Jack Kolff et al., "The Artificial Heart in Human Subjects" 1984 15 5 Jack G. Copeland , III, et al., "The Artificial Heart: What Next?" 1983 15 6 Kenneth A. Solen et al., "Assessment of Blood Microemboli Dynamic Development Using A Calf Ex-Vivo Left Ventricular Assist Device Model" 1990 15 7 Jack Kolff et al., "Assessment of the Ventricular Function of an Artificial Heart In Vivo" 1975 15 8 Robert K. Jarvik et al., "The Beat Goes On: Status of the Artificial Heart, 1977" 1978 15 9 Chisato Nojiri et al., "Blood Compatibility of PEO Grafted Polyurethane and HEMA/Styrene Block Copolymer Surfaces" 1990 15 10 R De Paulis et al., "Bloodpumps" 1986 15 11 R. De Paulis et al., "Blood Pumps as a Bridge to Cardiac Transplantation: Characteristics and Development" 1989 15 12 Don B. Olsen et al., "Blood Pump with a Magnetically Suspended Impeller" 1985 15 13 R. Gaykowski et al., "Bridging Cardiac Transplantation with a Total Artificial Heart" 1985 15 14 Gregory L. Burns et al., "The Calf as a Model for Thromboembolic Events with the Total Artificial Heart" 1987 15 15 Ruggero De Paulis et al., "Cardiectomy for Implantation of a Total Artificial Heart: A Modification" 1987 15 16 Geroge M. Pantalos et al., "Characterization of Natural and Total Artificial Heart Acceleration" 1989 15 17 S. D. Hughes et al., "Comparative Hematological Data From Animals Implanted with a Total Artificial Heart Containing Different Valves" 1985 15 18 Robert K. Jarvik et al., "Criteria for Human Total Artificial Heart Implantation Based on Steady State Animal Data" 1977 15 19 Robert K. Jarvik et al., "Comparison of Pneumatic and Electrically Powered Total Artificial Hearts In Vivo" 1978 15 20 Don B. Olsen et al., "Continuous Blood-Flow Pumps with Internal and External Motors" 1988 15 21 Don B. Olsen et al., "Control Systems for the Electric Heart" 1990 15 22 Kevin B. Murray et al., "Design and Functional Characteristics of Blood Pumps" 1984 15 23 George M. Pantalos et al., "Development of Pneumatically Driven Total Artificial Hearts Made By Vacuum Forming" 1986 15 24 Y. Taenaka et al., "Diagnosis of Mechanical Failures of Total Artificial Hearts" 1985 15 25 S. F. Mohammad et al., "Enhanced Bacterial Adhesion on Surfaces Pretreated with Fibrinogen and Fibronectin" 1988 15 26 Don B. Olsen et al., "The Experimental Total Artificial Heart in Transition to the Clinical Arena" 1981 15 27 Don B. Olsen et al., "Fabrication, Implantation, and Pathophysiology of the Total Artificial Heart in Calves for 6 Months" 1979 15 28 Pratap S. Khanwilkar et al., "Future Prospects for a Totally Implantable Artificial Heart" 1992 15 29 Don B. Olsen et al., "The Haemocompatibility of Fibril-Coated and Smooth Silastic Materials Compared with Polyurethanes in Total Heart Replacement" 1980 15 30 Don B. Olsen et al., "Heart Block in Sheep" 1966 15 31 Masayuki Kinoshita et al., "Hemodynamic Influence of LVAD on Right Ventricular Failure" 15 32 S. F. Mohammad et al., "Heparin Neutralization of Antiplatelet Effect of Aspirin and Dipyridamole" 1988 15 33 Don B. Olsen et al., "A History of Artificial Heart Research, 1967 to the Present, at the Institute for Biomedical Engineering, University of Utah" 1988 1998 15 34 Jacob Kolff et al., "History of Coagulation Defects in Long-Term Surviving Calves with Total Artificial Hearts" 1976 15 35 Gregory L. Burns et al., "Immune Response Changes with Blood Pump Use in Calves" 1989 15 36 Kevin D. Murray et al., "Implantable Pneumatic Artificial Hearts" 1991, 1996 15 37 Don B. Olsen et al., "Implantation and Pathophysiology of the Total Artificial Heart in Calves Living From One to Six Months" 1978 15 38 Don B. Olsen et al., "Implantation of the Total Artificial Heart by Lateral Thoracotomy" 1977 15 39 Chisato Nojiri et al., "Improved Blood Compatibility of PEO Grafted Polyurethane and HEMA/Styrene Block Copolymer Surfaces" 1989-1990 15 40 Jacob Kolff et al., "The Improving Hematologic Picture in Long-Term Surviving Calves with Total Artificial Hearts" 1979 15 41 Don B. Olsen et al., "Indeterminate Circulatory Support with the Artificial Heart" 1982 16 1 K. D. Murray et al., "Infection in Total Artificial Heart Recipients" 1983 16 2 Paul Didisheim et al., "Infections and Thromboembolism with Implantable Cardiovascular Devices" 1989 16 3 W. S. Pierce et al., "Intractable Congestive Heart Failure: Is there a Role for Mechanical Circulatory Assistance?" 1981 16 4 Richard K. Wampler et al., "In Vivo Evaluation of a Pheripheral Vascular Access Axial Flow Blood Pump" 1988 16 5 Eisuke Tatsumi et al., "In Vivo Long-Term Evaluation of Utah Electrohydraulic Total Artificial Heart" 16 6 Willem J. Kolff et al., "Lessons Learned from Dr. Barney Clark, the First Patient with an Artificial Heart" 1983 16 7 A. J. Pijl et al., "Loss of Anticoagulant Effect of Heparin During Circulation of Human Blood in Vitro" 1990 16 8 Jacob Kolff et al., "The Mechanical Heart on the Medical Horizon" 1975 16 9 Bang Y. Chiang et al., "Microbial-Infected Thrombus in Total Artificial Heart Animals" 16 10 Byoung G. Min et al., "A Moving-Actuator Type Electromechanical Total Artificial Heart - Part I" 16 11 John W. Holfert et al., "A New Connector System for Total Artificial Hearts" 1987 16 12 Jack Kolff et al., "The Nuclear Heart" 1976 16 13 Don B. Olsen et al., "Organ Function" 16 14 S. F. Mohammad et al., "Preferential Attachment of Bacteria on Adherent Thrombi In Vivo" 1990 16 15 J. M. Grevelink et al., "Pulmonary Artery to Pulmonary Artery Shunt" 1985 16 16 S. F. Mohammad et al., "Reduced Platelet Adhesion and Activation of Coagulation Factors on Polyurethane Treated with Albumin-IgG Complex" 1986 16 17 Don B. Olsen et al., "Registry and Tabulations of Orthotopic Total Artificial Hearts in Humans" 1987 16 18 Don B. Olsen et al., "The Role of Cardiac Valves in Artificial Heart Performance" 1979 16 19 M. Keith Sharp et al., "Sensitivity of the Artificial Heart to Changes in Vascular Resistance" 1989 16 20 Don B. Olsen et al., "State-of-the-Art and Clinically Applied Pneumatic Artificial Hearts" 1986 16 21 Don B. Olsen et al., "Surgical Approach to Bovine Fetal Catheterization and Hemodynamics" 1968 16 22 Hiroyuki Fukumasu et al., "Surgical Implantation of the Jarvik-5 Total Artificial Heart in a Calf" 1979 16 23 Don B. Olsen et al., "The Total Artificial Heart" 1984 16 24 Rugero De Paulis et al., "The Total Artificial Heart: A Better Model to Study the Hemodynamic Effect of Protamine" 1987 16 25 Don B. Olsen et al., "The Total Artificial Heart: From Initial Application to Therapeutic Option" 1997 16 26 Rugero De Paulis et al., "The Total Artificial Heart: Indications and Preliminary Results" 1987 16 27 Don B. Olsen et al., "The Totally Implantable Artificial Heart" 1990 16 28 Don B. Olsen et al., "Twin Calves, Total Artificial Heart, Cardiac Transplantation" 1983 16 29 Kevin D. Murray et al., "The Use of Calves and Sheep as Total Artificial Heart Recipients" 1985 16 30 R. Jarvik et al., "Venous Return of an Artificial Heart Designed to Prevent Right Heart Syndrome" 1974 16 31 John R. Rowles et al., "Ventricular Assist and Total Artificial Heart Devices for Clinical Use: State of the Art in 1992" 1993 16 32 Christof Westenfelder et al., "Volume Homeostasis in Calves with Artificial Atria and Ventricles" 1990 16 33 Manuscripts and Publishing Artificial heart manuscript 2004 17 1 Barney Clark manuscript 1947-1998 17 2-4 Blood pumps manuscript 1999-2002 17 5 Editorial review 1989-1993 17 6 Ghost writers 1983-2008 17 7 Publishers 2009-2010 17 8 Publication general index 1969-2002 17 9 Workshop 2007 17 10 People files, A-Z III Arthur C. Ackerman 1986-1987 18 1 Michael Alder 1989 18 2 Richard Alder 1986 1990 18 3 Paul Eugene Allaire 1995 18 4 Gary Allen, M.D. 1992-1993 18 5 Frank Altieri 1989 18 6 Salim Aziz 1994 18 7 Earl Bakken 2006 18 8 Jared Beesley 18 9 Forrest M. Bird 1987 18 10 William E. Bond 2009-2011 18 11 Harvey S. Borovetz 1993 18 12 Fernando Juan Boullon 1981-1993 18 13 Gunter Bramm 1982-2001 18 14 Gunter Bramm and Paval Novak 1984-1998 18 15 Thomas E. Brust and Lyle Joyce 1987-1988 18 16 John Bullock 2004 18 17 Christian Cabrol 1989 19 1 Karin Caldwell 1988 19 2 Michael J. Carmichael 1986-1987 19 3 Nancy Thrasher Cherry 1988 19 4 Bang-Yu Chiang 1988-1990 19 5 Paul Citron 1988 19 6 Una Loy Clark 1986-2006 19 7 Truman Clawson 1995-1997 19 8 Denton A. Cooley 2003 19 9 Jack G. Copeland 1985-1990 19 10 John J. Creatura 1992 1994 19 11 Shane Crounse 2008 2010 19 12 Don Dame 1992 19 13 Paul Davis 1973 19 14 Steven W. Day 2003-2011 19 15 Michael E. De Bakey 1934-2002 19 16 Walter Dembitski 1991 1999 19 17 Vladimir Petrovich Demikhov 1960 1969 19 18 William DeVries 1978-2009 19 19 Paul Didisheim 1979 20 1 Donald B. Doty 1991-1992 20 2 John Doty 1985-2008 20 3 David James Dries 20 4 Robert C. Eberthart 1992 1999 20 5 Joanne Elser 1991 20 6 Terrance A. English 1984-1985 20 7 Colleen G. Farmer 2005 2007 20 8 Rene G. Favaloro 1980-1981 20 9 Robert B. Fine 1996 20 10 Jerrold Foote 1991 20 11 O. H. "Bud" Frazier 1984-2007 20 12 William H. Frist 1982 20 13 William A. Gay, Jr. 1984-1991 20 14 Walter P. Gnemi 1989 20 15 Leonard Golding 2003 21 1 Michael Goldowsky 1994-2003 21 2 Lamar Gray 1998 21 3 Bartley Griffith 1985 21 4 Stewart Grow 1990 1993 2004 21 5 Laurence A. Harker 1988 21 6 Orrin G. Hatch 1990-2007 21 7 Axel Haubold 1988 21 8 William V. Healey 1994 21 9 Peter Heimes 1979-1982 21 10 Ewald Hennig 1980 1987 21 11 Robert H. Hinckley, Jr. 1979 1981 21 12 Garron Hobson 1961 2009-2012 21 13 John Holfert 1983-1992 21 14 Arthur H. Holmgren 1981 21 15 David L. Holmberg 1979-1990 21 16 Dean A. Holt 1969-1998 22 1 Jon M. Huntsman 2003 22 2 Jim Isaacson 1986-1992 22 3 Valentin M. Izraelev 1997-2001 22 4 Gordon B. Jacobs 2000 22 5 Steve Jacobson 1980, 1983 22 6 Robert Jarvik 1973-2007 22 7 Lyle Joyce 1984-2006 22 8 Wilbert Keon 1988-1996 22 9 Jack Kerlin 1988-1993 22 10 Thomas R. Kessler 1981-1982 23 1 Pratap Khanwilkar 1990-1998 23 2 Chi Han Kim 1989 23 3 Sung Wan Kim 1988-1989 23 4 Richard K. Koehn 1992-1993 23 5 Jack Kolff 1974-1986 23 6 Robert L. Kormos 2000 23 7 Ken M. Kosak 1999 23 8 Mehmet Kosem 23 9 Kristine Knutson 1990 23 10 Ehud Krisher 1988 23 11 Clifford S. Kwan-Gett 1967-2008 23 12 Rodney J. Landreneau 1992 23 13 Perry Lane 1987-1991 23 14 Alan M. Lansing 1985-1991 23 15 Didier Lapeyre 1979 23 16 David Lederman 1984, 1989 23 17 Claude Lenfant 1983-2002 23 18 David L. Lentz 1981-1982 23 19 Barron Lerner 2004 23 20 Boris Mikhail Leschinsky 1992 23 21 Mark M. Levinson 1987 23 22 C. Walton Lillehei 1982 24 1 Charles A. Lindbergh 1935 24 2 Domingo Liotta 1985-1991 24 3 James W. Long 1987-1999 24 4 David L. Ludwig 1988-2001 24 5 Alvin Marden 1995-1998 24 6 Pierre Marrion 1977-1983 24 7 William Martin 1993-1996 24 8 James C. McRea 1991 24 9 Jay W. Mason 1989 24 10 Edward Massey 1995 24 11 Alan H. Menkis 1989-1991 24 12 Edward L. Menning 1991 24 13 Roger C. Millar 2000 24 14 Byoung G. Min 1988-1990 24 15 Syed F. Mohammad 1985-2010 24 16 John C. Moise 1985 1988 24 17 Charles H. Moore 1981 1993 25 1 Jerry Moore 1989-1995 25 2 Rodman Moorehead 1987 25 3 J. D. Mortenson 1989-1991 25 4 Burkhart Muller 1986 1993 25 5 Michael R. Muller 1990 25 6 Kevin D. Murray 1981-2010 25 7 Tofy Mussivand 1991 1994 25 8 John Nanas 1981-1989 25 9 Jose A. Navia 1980 25 10 Mike Nielsen 1980 25 11 Steve D. Nielsen 1982-1987 25 12 Thomas J. Nikolai 1992-2001 25 13 Chisato Nojiri 1987 25 14 George P. Noon 1993-2005 25 15 John C. Norman 1980 1984 26 1 Richard C. Normann 1993 26 2 Vaughn W. North 1987-1990 26 3 Yukihiko Nose 1974-2009 26 4 Emery Nyilas 1978-1981 26 5 John J. Pacella 1999 26 6 George M. Pantalos 1981-1993 26 7 Richard S. Pauliukonis 1981 26 8 D. Glenn Pennington 1984-1985 26 9 David W. Pershing 1989 26 10 Chase Peterson 1988-1990 26 11 Steven Joseph Phillips 1990-2002 26 12 Winfred M. Phillips 1978-1980 26 13 T. Boone Pickens 1986-1987 26 14 William Pierce 1979-1998 26 15 Victor L. Poirier 1991 26 16 Ronald Pugmire 1992 26 17 Kunxi Qian 1983-1992 27 1 Reed D. Quinn 27 2 Gerhard Rakhorst 1988-1991 27 3 Bruce A. Reitz 1980-1981 27 4 Robert L. Replogle 1981 27 5 Helmut Reul 1994 27 6 Wayne Richenbacher 1989-1992 27 7 Jerome B. Riebman 1986-1994 27 8 Bryan M. Romney 1989 27 9 Gideon Ruttenberg 1990 27 10 Heinrich Schima 1997-2002 27 11 James R. Scott 1989 27 12 Jim Scott 1989-1991 27 13 William J. Seare 1991-1995 27 14 Craig Selzman 1989-2010 27 15-16 Keith Sharp 1986-1991 28 1 Lawrence W. Shearon 1981 28 2 Arthur K. Smith 1991-1992 28 3 Lee Smith 1979 1984 28 4 Edward D. "Mark" Staples 1990 28 5 Albert Starr 1993 28 6 Robert L. Stephen 1988-1994 28 7 Yoshiyuki Taenaka 1982-1996 28 8 Eisuke Tatsumi 1990 28 9 Dr. Tector 1985 28 10 Herwig Thoma 1977-1983 28 11 Amy L. Throckmorton 2007 28 12 Ken O. Thornton 1989-1992 28 13 Marko Turina 1978-1982 28 14 Akif Undar 2003 28 15 Felix Unger 1986-1988 28 16 Andreas F. VonRecum 1979-1981 28 17 Richard K. Wampler 1986-2001 28 18 Bruce D. Ward 1988 28 19 Robert S. Ward 1987-1991 28 20 John T. Watson 1985-1996 28 21 Christof Westenfelder 1984-2011 28 22 Maurice White 1991-1992 29 1 Frederick Marlin Wilson 1990-1993 29 2 Paul Winchell 1963-2005 29 3 Ernst Wolner 1995 2009 29 4 Huang Yimin 1999-2000 29 5 Winslow Young 1988 1993 29 6 Hans Zwart 1982 29 7 Willem J. Kolff 1978-2006 30 Business Files A-Z IV Abiomed 1988-2002 31 1 ABBACOR, Incorporated 1991-2001 31 2 Advanced Interventional Technologies Laboratories 1994-1996 31 3 Advanced Medical Systems, Incorporated 1991 31 4 Alliance for Engineering in Medicine and Biology 1989-1992 31 5 American Institute of Medical and Biological Engineering 1992 31 6 American Society for Artificial Internal Organs (ASAIO) 1989-2000 32 1 ASAIO Bionics 2001-2005 32 2 APEX Medical, Incorporated 1992-2000 32 3-5 Baxter International, Incorporated 1994-1997 33 1 Baxter World Trade Corporation 1994 33 2 Becton Dickinson Vascular Access 1993-1994 33 3 Beijing Institute of Heart, Lung and Blood Vessel Diseases 2000 33 4 Berlin Heart Institute 33 5 Bioelastics Research, Limited 1993 33 6 Centers of Excellence 1985-1991 33 7 Cleveland Clinic Foundation 1988-1998 33 8 Colorado State University 1986 2009 33 9 C. R. Bard, Incorporated 1993 33 10 Deseret Foundation 1994-1995 33 11 Dow Chemical Company 1984-1992 33 12 Falcon Technologies, Incorporated 1986-1993 34 1 Food and Drug Administration (FDA) 1980-1989 34 2-3 Foster-Miller Technologies 1999 2001 34 4 Heart and Lung Institute 1996-1997 34 5 Heart and Lung Research Foundation 1997-1998 34 6 Institute of Medicine 35 1 Intermountain Healthcare (IHC) 1993-1994 35 2 International Academy for Artificial Organ Pioneers 2003 35 3 International Center for Medical Technologies 2002 35 4 International Faculty for Artificial Organs 1990 35 5 Kolff Medical, Incorporated 1981-1989 35 6 Meadox Medicals, Incorporated 1993 36 1 Medtronic, Incorporated 1969-1998 36 2-3 National Academy of Science, Institute of Medicine 1988-1991 36 4 Nimbus Pump Experiments 1989 36 5 Novacor 1987-1999 36 6 Paralax Group Incorporated 1996 37 1 Pennsylvania State University 1993-2001 37 2 Pfizer, Incorporated 1973-2008 37 3 Rubicon, Incorporated 2002 2007 37 4 Saint Jude Medical 1989-1994 2005 37 5 Saint Marks 1973-1986 37 6 Sarcos Research Corporation 2003 37 7 Small Business Innovation Research (SBIR) 1985-1986 37 8 Symbion, Incorporated 1983-1990 38 1-3 Terumo Corporation 1998-2005 38 4 Thoratec 1990 2008 38 5-6 Transonic Systems, Incorporated 1992 1994 39 1 Triton Technology, Incorporated 1993-1994 39 2 University of Virginia 2002-2003 40 1 Utah Artificial Heart Institute 1973-2007 40 2 Whalen Biomedical Incorporated 1999 40 3 W. L. Gore and Associates 1981 2001 40 4 World Heart Corporation 1992-2008 40 5 Business Files, Artificial Heart Research Laboratory (AHRL) Contacts 1988-1993 41 1 Documentation 1986-1987 41 2 Electrohydraulic total artificial heart 1986 1989 41 3 Nimbus hemopump experiment 1989 41 4 Organizational charts and policies 1989-1993 41 5 Ottawa Heart Institute 1989-1992 41 6 Planning, project priority 1990-1993 41 7 Principles of manufacturing and design 1988 41 8 Project overviews 1988-1991 41 9 University of Utah 1988-1994 41 10-11 Business Files, CardioWest Technologies Executive summary 1996 42 1 Exhibits 1996 42 2 FDA 2001 2004 42 3 Investigational device exemption application G920101 for the CardioWest C-70 total artificial heart used in a bridge to transplant application 1992 42 4 Progress report 1995 42 5 General materials 1992-2007 43 1 Business Files, Medforte Research Foundation 1988-2009 44 Business Files, MedQuest Agreements: UAHI, MQP, UVA 1995-2001 45 1 Al Mardsen 1998 45 2 Budget and financing 1996-2003 45 3 Business plan 1996 45 4 Continuous flow VAD, SBIR 1992-1996 45 5 Heart Lung Institute 1998 45 6 Leadership in long-term mechanical circulatory support 1995 45 7 Letterhead 45 8 Lexco 1991-1999 45 9 License agreement with University of Utah Research Foundation 1998 45 10 Marketing 1994 45 11 Meeting materials 1999-2001 46 1 Minnesota Heart Company 46 2 MQP Puncher / Rafael 2002-2003 46 3 Negotiations for UAHI and MQP continued cooperation 1999-2002 46 4 Saint Jude Medical 1994 46 5 Sarns, Incorporated 1995 46 6 Stocks and shareholders meetings 2004 46 7 Utah Artificial Heart Institute subcontract agreement 1999 46 8 General materials 1981-2002 47 1-4 Business Files, MicroMed Budgets 1998-2000 48 1 DeBakey VAD 1994-2003 48 2-4 Physiology study protocols 1997-1998 48 5 Quality assurance-GLP 1999 48 6 Valved conduit 1997-1999 48 7 General materials 1997-2003 49 1 Business Files, University of Utah Institute for Biomedical Engineering (IBE) Audit 1999 50 1 British Petroleum Co. and Donald Braben 1986-1988 50 2 Ross Perot 1987 50 3 Development efforts 1985-1989 50 4 General materials 1986-1992 50 5-6 Research materials V Artificial heart research: history and general 1963-2007 51 Artificial heart research: history and general 1963-2007 52 Artificial heart research: clinical 1974-1990 53 Blood pumps Centrifugal and electromagnetic blood pumps 1960-2006 54 1 Hemolysis in rotary blood pumps 1965-1997 54 2 Rotary blood pumps control 1998-1999 54 3 Rotary blood pumps history 1839-2007 54 4 Continuous-flow Ventricular Assist Device (CFVAD) Affiliations 1998-1999 55 1 Artificial heart project meetings 1992 55 2-3 Artificial heart system 1987-1992 55 4 Blood pumps 1993-1994 55 5 Continuous flow pump 1988-1990 55 6 Finance 1991-1993 56 1 Patents 1987-2000 56 2-3 Physiologic controllers 1997-2001 56 4 Projects 1992 56 5 University of Virginia 1991-1995 56 6 Continuous-flow Ventricular Assist Device (CFVAD) 1996-2000 57 Electrohydraulic Total Artificial Heart (EHTAH) Abiomed 58 1 Acute experiment 1990 58 2 Automatic control algorithm 58 3 Chronic EHTAH 20 experiment 1990 58 4 Contract materials 1988-1989 58 5-6 Development 58 7 EHTAH 20 implants 1990 58 8 Energy converter 1993 58 9 Fit trials 1990 58 10 Inter atrial shunt 1990 59 1 In vivo experiment 1983-1990 59 2 Memoranda 1990 1993 59 3 NIH representative 1993 59 4 Population information 59 5 Presentation 59 6 Pressure transducer failure 1990 1992 59 7 Principal investigator meetings 1989-1990 59 8 Quality issues 1990 59 9 Quarterly report 1990 59 10 Robocalf 1990 59 11 Symposium presentation 1989 59 12 Transcutaneous energy transmission system 1992 59 13 Physiologic controllers Continuous-flow artificial heart pumps proposal and Houston Wood 2000 60 1 Impeller speed control for rotary blood pumps 1996-1999 60 2 LVAD utilizing pressure sensing 2000-2002 60 3 Rotary blood pumps 1963-2003 61 1-2 General materials 1968-2002 62 1-4 Total Artificial Heart Replacement (TAH) Abiomed 1989-1990 63 1 Anatomic fit TAH/VAD 1965-1991 63 2 Automatic controls for TAH 1972-1993 63 3 Baylor 1993 63 4 Characteristics 1989 1995 63 5 China 1989 63 6 Cleveland Clinic 1987-1990 63 7 Clinical 1981-2009 64 1 Clinical updates, Symbion 1986-1988 64 2 Clinical VAD and TAH history 1966-2002 64 3 Comparing devices 1998-2001 64 4 Computer model 1973-1989 64 5 Control systems 1968-1993 64 6 Developers and designers 1965-1990 64 7 Division of Artificial Organs (DAO) policies 1983 64 8 Economics and ethics 1986-1988 65 1 Experimental 1991 65 2 Future of TAH 1989 65 3 Hemodynamics 1989 65 4 Name credit for artificial heart 1983-2010 65 5 Neurohormonal responses 1985 65 6 Number of patients 1986-1987 2006 65 7 Patents 2002 2007 65 8 Patient survey 1986-1988 65 9 Publicity 1982-2009 65 10 Registry 1986-2004 65 11 Review 1990 66 1 Right-left ventricular balance 1990-1991 66 2 Skeletal muscles 1987 1989 66 3 Utah-100 1978-1991 66 4 General materials 1966-2004 67 General materials 1966-2004 68 Utah-100 artificial heart Eliptical heart 1983-1987 69 1 FDA 1987-1992 69 2-3 IDE application 1980-1991 69 4 License agreement 1982 1986 69 5 Publications 1983-1986 69 6 Sales/Bill Gay 1987 69 7 General materials 1985-1987 69 8 Ventricular Assist Device (VAD) Cleveland Clinic, Nimbus 1982-1989 70 1 DeBakey VAD 1994-2001 70 2-3 EVAD project team 1989-1990 70 4 FDA 1992-2000 70 5 Heart/VAD controller schematics 70 6 Hemocompatability 1996-1999 70 7 Hemodynamics 1998-2000 71 1 LEV-VAD specifications 2001 71 2 Left ventricular assist system 1991 1993 71 3-4 Magnet-LVAD patent issues 2010-2011 71 5 Magneto hydrodynamic pump-VAD 1987-2003 71 6 Manufacturing the Olsen VAD 2003 72 1 Massachusetts General Hospital, Abiomed 1982-1989 72 2 MicroMed studies 1995 2000 72 3 Pennsylvania State University, Thoratec 1982-1990 72 4 Performance 2000 72 5 Physiologic controller 1999 72 6 Stanford University, Novacor 1982-1989 72 7 Texas Heart Institute, Thermedics 1982 1984 72 8 Totally implantable 1999-2000 72 9 Vienna patient 1999 72 10 Subject files, A-Z Airflow 1981-1985 73 1 Allegheny-Singer 1992-2001 73 2 Alveolar surfactant 73 3 Angiogenesis 1987-2002 73 4 Animal model information 1971-1978 73 5 Animals implanted with CF3, 4, 5 73 6 Antithrombotic agents 73 7 Artificial eye 1974-1976 73 8 Artificial hearing 1982-1989 73 9 Artificial heart evaluation 1972-1973 73 10 Artificial Heart Technologies Program 1995-1997 73 11 Artificial kidney 1987 73 12 Artificial liver 1986-1989 73 13 Artificial pacemakers 1989 73 14 Artificial penis 1989 73 15 Artificial speech 1989 73 16 Artificial vision 1988-1989 73 17 Atrial natriuretic factor (ANF) 1979-1992 74 1-3 Atrial septal defect 74 4 Autologous fibrin sealant, phase I 2002 74 5 Auxiliary ventricles 1963-1982 74 6 Baylor gyro pump 1991-1999 75 1 Biocompatibility of Ventricular Assist Device (VAD) 1996-1999 75 2 Bjork-Shiley valve 1979-1990 75 3 Blood flow in bearing spaces 1996-1997 75 4 Calf physiology and artificial heart 1977-1980 75 5 Calf-sitter protocols 1987 75 6 Carcinogenesis-solid state implants 1964-1973 75 7 Cardiac assist devices 1988 75 8 Cardiac output monitor and diagnostic unit (COMDU) 1983-1989 75 9-11 Cardiovascular dynamics 1988-1989 75 12 Circulatory assist devices 1949-1974 76 1 Circulatory Support System Model IIIE, user's manual 1988 76 2 Chronic LVAD 1989 76 3 Computers 1989-1993 76 4 Cross-linking and modifications 76 5 Data safety and monitoring 1999 76 6 Design controls 1999 2004 76 7 Dilated CM recovery with MCSS 1996-2002 76 8 Doppler flow velocemetry 1987-1990 76 9 Driver 1989-1993 76 10 Economics 1990 77 1 Edward heart valve testing 2005 2005 77 2 Endothelial cells 1989-1990 77 3 Ethical communications 1986 1988 77 4 Ethics and animals 1982-1993 77 5 Ethics 1983-1992 77 6 Experimental data: bladder 1982 77 7 Factors influencing rith-left ventricular filling volumes 77 8 Fibrin glue 1992 77 9 First experiences with short and long-term survival with the Czechoslovak TAH-TNS-BRNO-I 1978 1982 77 10 Gould recorders and monitoring 1983 77 11 Health care costs 1991-1993 77 12 Heart centrifugal pump 1968-1993 77 13 Heart failure experiment 1989 77 14 Heart failure/models 1969-1999 77 15 Heart valves 1989 77 16 Hemodynamic studies of artificial heart systems 1990 78 1 Hemopump and R. Wampler 1987 78 2 Heparin filter 1989 78 3 Heparinized surfaces 1988-1991 78 4 History of cardiac replacement 1969-2007 78 5 Horses/ponies 1972-1988 78 6 Hypothermia 1955-2004 79 1-3 Induced cardiac failure models 1969-2003 79 4 Intraaortic balloon pumping (IABP) 1978-1990 80 1 Ischemia 1990 80 2 Jarvik heart 1990-2000 80 3 Jarvik-7R total artificial heart clinical training manual 1987 80 4 Kolff's 65cc clamshell 1989-1990 80 5 Laboratory automation 1990 80 6 Magnetic bearings 1989 1997 81 1 Magnetically suspended and rotated rotor patent materials 1987-1997 81 2 Mechanical circulatory support bridging to transplant 1969-1993 81 3 Minimal invasive surgery 1999 81 4 Mitral valve 1961-1979 81 5 Mock circulation instruction manual 1977 1994 81 6 New artificial hearts 1967-1978 82 1 Organ presentation 1990 82 2 Outline of artificial organs 1962 82 3 Pediatric circulatory support: an FDA perspective 2005 82 4 Pediatric hearts 1970-1989 82 5 Pharmacology 1989 82 6 Physiological responses and the total artificial heart 82 7 Pilot study: new magnetically suspended LEV-VAD 82 8 Platelets 1990 82 9 Platelets/growth factors, phase II 2002 82 10 Pneumatic artificial heart: driver, monitoring 1974-1990 83 1 Polymers/plastics 1994 83 2 Portable pneumatic driver 1986-1997 83 3 Power supplies and controls: Mock circulation/TAH 1968-1984 83 4 Pressure monitoring 1983 1986 83 5 Pressure tranducer testing 1990 83 6 Prostate cancer 83 7 Proposal to establish a center for biomedical polymers at the University of Utah 1991 1993 83 8 Pulmonary embolism and postmortem angiography 1957-1970 84 1 Pulsatile/non pulsatile 1993-2006 84 2 Scientific frontiers 1989 84 3 SKF proposal 1996-1997 84 4 Societies 1984-1985 84 5 Statistics in medicine 1990 84 6 Study of heparin removal during bypass 1990 84 7 Survival time graph 84 8 Suture line testing 1975 84 9 Telemetry 1972-1992 84 10-11 Thermal management 1989 84 12 TP 508 2001 84 13 Transplantation 1968-1982 85 1 Trivia 85 2 Trypanosomes 1976-1980 85 3 Vibroacoustic monitoring 1996-1997 85 4 Equipment Cine equipment request 1979 86 1 Device standards 86 2 Distributors 1989-1990 86 3 Millar catheters 1990 1993 86 4 General materials 1986-1988 86 5 Research articles by others, A-Z

The articles located in boxes 87-93 are arranged alphabetically by the author's last name.

 Aar-Dri 1979-2001 87 Far-Lyn 1972-2007 88 Mar-Rou 1977-2000 89 Sim-Tod 1978-2007 90 Wak-Zwa 1962-1997 91 Research articles by Willem J. Kolff with others 1955-1994 92 Research articles by Willem J. Kolff with others 1955-1994 93 Research articles by publication, Ame-Wee 1977-1997 94 Pump models, plaques, and news clipping 1991 1995 2006 95